CHEM 240 - Introduction to Bioanalytical Chemistry (Spring 2008)

Lecture: 9:00-9:50 am, MWF in 003 Hughes (Sect. 02, CRN 20749) .
Instructor: Jeff Cronk E-mail: cronk@gonzaga.edu   Office: Hughes 234.
Office Hours: M,W, Th 4-5 pm; M, F 12-1 pm (tentative) and by appointment
Required Texts: 1. D.C. Harris - Exploring Chemical Analysis (3rd edition)  2. D.W. Oxtoby - Introduction to Bioanalytical Chemistry (custom publication covering kinetics and thermodynamics - available at GU bookstore only)
Other required materials: scientific calculator
Corequisite: You must be concurrently enrolled in both CHEM 240 and 240L. If you drop one, you must drop the other as well.
Enter the CHEM240 course website


  Class schedule
(under revision, 01-07-08)
MONDAY WEDNESDAY FRIDAY
 

WEEK 1
16, 18 January

( Lectures 1, 2 )

 

16 January.
Introduction

18 January. Chemical measurements and the
analytical method


WEEK 2
21, 23, 25 January
( Lectures 3 , 4 )
MLK Holiday

23 January.
Statistical treatment of experimental data

25 January.
Statistical treatment of experimental data


WEEK 3
28, 30 January; 1 February
( Lectures 5 - 7 )
28 January.
Acid-base chemistry:
Brønsted-Lowry
30 January.
Acid-base equilibria:
Weak acids and bases
1 February.
Acid-base chemistry:
Buffers

WEEK 4
4, 6, 8 February
( Lectures 8. 9, 10)
4 February.
Acid-base chemistry: Titrations
6 February.
Acid-base chemistry:
Polyprotics

8 February.
Titrations of polyprotic
acids and bases


WEEK 5
11, 13, 15 February
( Lectures 11, 12 )
11 February.
Analysis of Polyprotic Titrations
13 February
EXAM 1
15 February.
Principles of
spectrophotometry

WEEK 6
18, 20, 22 February
( Lectures 13, 14 )
President's Day
Holiday
20 February.
Applications of spectrophotometry
22 February.
Applications of spectrophotometry

WEEK 7
25, 27, 29 February
( Lectures 15, 16, 17 )

25 February.
Standard addition
Internal standards

27 February.
Elemental analysis:
ICP
29 February .
Electrochemistry:
Reduction potentials

WEEK 8
3, 5, 7 March
( Lectures 18, 19, 20, )
3 March.
Electrochemistry:
Redox reactions
5 March.
Applications of
electrochemistry
7 March.
Electrochemistry:
pH electrodes

WEEK 9 - Spring Break (10 -14 March)
 
    MONDAY WEDNESDAY FRIDAY

  WEEK 10
17, 19, 21 March
( Lectures 21, 22 )
17 March.
Electrochemistry:
The oxygen electrode
19 March.
Principles of
chromatography
21 March
Good Friday
Holiday

  WEEK 11
24, 26, 28 March
( Lectures 23, 24 )
24 March
Easter Holiday
26 March.
Review session
for Exam 2
28 March
EXAM 2

  WEEK 12
31 March, 2, 4 April
( Lectures 24, 25, 26 )
31 March.
Applications of
chromatography
2 April.
Chromatography;
Electrophoresis
4 April.
Gel electrophoresis
and SDS-PAGE

  WEEK 13
7, 9, 11 April
( Lectures 27, 28, 29 )
7 April.
Kinetics: Rate laws
and reaction order
9 April.
Experimental kinetics
rate data
11 April. Fourier
transform infrared
spectroscopy (FTIR)

  WEEK 14
14. 16, 18 April
( Lecture 30, 31, 32 )
14 April. Kinetics:
Reaction mechanisms
& rate laws
16 April.
Kinetics: Catalysis
and enzymes
18 April.
Kinetics and
thermodynamics

  WEEK 15
21, 23, 25 April
( Lectures 33, 34 )
21 April.
Thermodynamics:
Enthalpy & state functions
23 April.
Differential scanning
calorimetry (DSC)
25 April
EXAM 3

  WEEK 16
28, 30 April, 2 May
( Lectures 35, 36, 37 )
28 April.
Thermodynamics:
Entropy & the 2nd law
30 April.
Thermodynamics:
Free energy & equilibria
2 May.
Thermodynamics
and living systems

FINAL EXAM - Wednesday 7 May 2008, 8:00 - 10:00 am
 

Course objectives: CHEM 240 introduces fundamental concepts of analytical chemistry, thermodynamics, and kinetics with the goal of providing the background necessary for working biologists, and is intended exclusively for biology majors. Major analytical topics that are covered include acid-base chemistry, titrations, spectroscopy, redox reactions and electrochemistry, and chromatography.

Grading: Your grade will be based on scores in three in-class exams (100 points each), a final exam (200 points), and quizzes or homework (100 points). (The laboratory grades are determined separately.) Grades will be assigned on the basis of percentage of possible points earned, according to the scale: 90-100 A-/A; 80-89 B-/B/B+; 70-79 C-/C/C+; 60-69 D/D+; <60 F. Note that adjustments to this scale may be made according to the class distribution of total scores and your level of class participation. NOTE: It is your responsibility to be familiar with and abide by GU's Academic Honesty Policy

Missed exams, quizzes, late homework: I will permit make-up exams and quizzes only for students with a legitimate, urgent excuse who have contacted me prior to the exam or quiz. I reserve the right to deduct points from homework that is turned in late

For further course information, consult the course website.