CHEM 440
Biochemistry I
J. D. Cronk   Syllabus [ Previous | Next ] Pick a lecture:
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Lecture 19. Hemoglobin

Monday 26 October 2009

Hemoglobin and allostery. Sequential model for cooperativity. Heterotropic factors influencing oxygen affinity of Hb: pH and carbon dioxide (the Bohr effect), 2,3 bisphosphoglycerate (BPG). Variant globin subunits (e.g. fetal Hb) have altered oxygen affinity; correlation of oxygen affinity with local and global (quaternary) structural changes.

Reading: BTS6 - Ch.7, pp.187-198.
19. Summary

Lecture {L} Summary

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Learning objectives

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References
 
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[ E-mail: cronk@gonzaga.edu ]