Lecture 27. Survey of coming attractions...
Thursday 2 May 2019
Where does a continued study of biochemistry lead us? The citric acid cycle, glycogen metabolism, and the glyoxylate cycle in plants. Oxidative phosphorylation, or the coupling of electron transport chain to ATP synthesis, is the culmination of bioenergetics. Other metabolic pathways and integration of metabolism.
Reading: Lehninger - Ch.19, pp.728-741.
Summary
Oxidative phosphorylation is the fundamental energy-yielding process underlying aerobic metabolism. Electrons derived from the catabolic reactions of the citric acid cycle (in the form of NADH or FADH2) are transferred to via a series of steps known as the electron transport chain (ETC). This intricate series of transfers that take place in eukaryotic cells at the inner membrane of mitochondria is an energy-releasing process. The energy of electron transfer is transduced into a transmembrane electrochemical gradient, which in turn provides the potential energy for the conversion of ADP and inorganic phosphate into ATP by ATP synthase.
Supplementary and additional resources: citric acid cycle; electron transport chain;